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The Top Five Safeguards Against Professional Patients and Duplicate Subjects in Clinical Trials

Clinical trials face an often-overlooked but critical threat: professional patients and duplicate subjects in clinical trials. These individuals move between studies—sometimes across different sponsors, therapeutic areas, or even countries—putting patient safety, data integrity, and trial outcomes at risk. Unfortunately, most traditional methods of protection fall short: These approaches are like putting a band-aid on a …

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Preventable Failures in GLP-1 and Obesity Clinical Trials: How VCT Protects Against Professional Research Subjects and Duplicate Enrollment

You never want to see a clinical trial fail. The consequences are enormous: And yet, many of these failures are preventable. A recent article highlighted a trial with unusually high discontinuation rates, particularly in the placebo group. Analysts were “puzzled.” I wasn’t. If a participant isn’t losing weight and suspects they’re on placebo, they can …

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Beyond Their Lane: How Verified Clinical Trials Detects Cross-Therapeutic Duplicate Subjects In Clinical Trials

In the clinical research world, it’s easy to assume that participants stay in their lane—only enrolling in studies within the same therapeutic area. The reality is far different. Research subjects often cross over between very different indications, creating hidden risks for trial integrity, data quality, and participant safety. These situations aren’t limited to professional subjects …

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Eliminating the Professional Patient Problem in Clinical Trials: Why Verified Clinical Trials Is the Global Standard

In today’s competitive and complex research environment, professional patients—individuals who enroll in multiple clinical trials either simultaneously or back-to-back—pose one of the greatest threats to data integrity, subject safety, and trial success. These individuals often participate for financial gain or repeated access to investigational therapies, disregarding protocol requirements such as washout periods or exclusion criteria. …

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Verified Clinical Trials: The Global Standard — and Only Comprehensive Solution — for Duplicate Subject Prevention in Clinical Trials

In modern clinical research, competition for eligible subjects is intense, protocols are increasingly complex, and timelines are tighter than ever. Across therapeutic areas, one persistent and costly threat continues to undermine trial integrity: duplicate and professional research subjects. These are individuals who enroll in multiple studies either at the same time or in rapid succession—often …

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Beyond Screening: Why Verified Clinical Trials Is Essential Throughout the Entire Research Lifecycle To Prevent Professional Patients In Clinical Trials

Preventing professional patients in clinical trials, duplicate research subjects, and dual enrollment in clinical trials isn’t just a Day 1 problem — it’s a long‑term necessity. In clinical research, subject risk is often assumed to be limited to eligibility at screening. But what happens after randomization? What about long-term follow-up, crossover phases, or open-label extensions? …

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“It’s You Again?” — The Professional Patient in Clinical Research

In the world of clinical trials, research sites occasionally have a strange feeling of déjà vu—”It’s you again?” That familiar face showing up for another screening visit may not just be coincidence. In fact, it’s often a warning sign of a growing issue in clinical research: professional patients and duplicate subjects in clinical research. These …

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Most therapeutic areas are under threat from duplicate research participants—and it’s costing everyone

Studies in clinical research show that duplicate or professional trial participants—individuals enrolling in multiple studies simultaneously—are far more common than many sponsors realize. Rates as high as 10% have been reported in therapeutic areas beyond psychiatry, including dermatology, ophthalmology, respiratory, and others. Each duplicate research subject can skew efficacy, safety, and overall trial integrity. The data: …

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Duplicate Research Subjects: The Silent Threat to Your Clinical Trial — And How Verified Clinical Trials Protects You

Clinical trials are complex, high-stakes endeavors where every detail matters — yet one hidden risk continues to undermine studies across all therapeutic areas: duplicate and professional research subjects. You may believe your internal checks, EDC reviews, or sponsor-specific solutions have you covered. The reality?Most systems only detect duplicate subjects after they’ve already dosed — or …

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